SUCCESSFUL GROWTH OF FRESH RETINOBLASTOMA CELLS IN CHORIOALLANTOIC MEMBRANE

Successful growth of fresh retinoblastoma cells in chorioallantoic membrane

Successful growth of fresh retinoblastoma cells in chorioallantoic membrane

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Abstract The authors developed a retinoblastoma model using fresh harvested cells from an enucleated eye that were transplanted in chick embryos (chorioallantoic membrane model).The transplanted Wound Care embryos were treated with escalating doses of Melphalan.This exploratory model was developed with the goal of testing drug sensitivity.

Our Boxes findings suggest this tumor model could be employed to personalize treatment for patients with retinoblastoma, especially those with bilateral and more refractory disease.

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